Previously, the only cation exchange resin available was sodium polystyrene sulfonate (SPS), which was approved in 1958, before manufacturers had to demonstrate both efficacy and safety. General: Patient advice: Risk factors for gastrointestinal adverse events were present in many of the cases including prematurity, history of intestinal disease or surgery, hypovolemia, and renal insufficiency and failure. Monitor patients who are sensitive to sodium intake (heart failure, hypertension, edema) for signs of fluid overload. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Advise patients who are taking other oral medication to separate the dosing of Sodium Polystyrene Sulfonate by at least 3 hours (before or after) [see Dosage and Administration (2.1), Warnings and Precautions (5.5), and Drug Interactions (7.1)]. A somewhat thicker suspension may be used, but do not form a paste. -A 15 g dose is equivalent to approximately 4 level teaspoons. Administer as a warm (body temperature) emulsion in 100 mL of aqueous vehicle and flush with 50 to 100 ml of fluid. -The efficiency of ion exchange is predicted to be around 33%, but is highly variable. Polystyrene sulfonates release sodium or calcium ions in the stomach in exchange for hydrogen ions. -Enema should be kept in the rectum for as long as possible and rectum should be washed with a cleansing enema after use. Small amounts of other cations such as calcium and magnesium may be lost during treatment. Sodium polystyrene sulfonate comes as a suspension and as an oral powder for suspension to take by mouth. We comply with the HONcode standard for trustworthy health information -. Sodium polystyrene sulfonte (Kayexalate) is one of a small number of medications used to remove potassium from the body. -Enemas should be suspended in 100 mL body-temperature vehicle prior to administration. The U.S. Food & Drug Administration (FDA) has warned that orally-administered Kayexalate should not be taken with any other oral medications because it may reduce the effectiveness of those drugs. Pms-Sodium Polystyrene Sulfonate; Descriptions. The nurse should identify which of the following entries as the correct format for the medication administration record (MAR)? Storage requirements: KAYEXALATE, brand of sodium polystyrene sulfonate is a benzene, diethenyl-polymer, with ethenylbenzene, sulfonated, sodium salt and has the following structural formula: The drug is a cream to light brown finely ground, powdered form of sodium polystyrene sulfonate, a cation-exchange resin prepared in the sodium phase with an . The sodium content is approximately 100 mg (4.1 mEq) per gram of the drug. -If using rectally, may require up to 2 quarts of cleansing solution. One level teaspoon contains approximately 3.5 g of Sodium Polystyrene Sulfonate and 15 mEq of sodium. -Store in an airtight container protected from light and heat. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Maximum dose: 15 g orally 4 times a day It can be administered orally or rectally as an enema. Administer other oral medications at least 3 hours before or 3 hours after Sodium Polystyrene Sulfonate. -Caution patients to avoid taking antacids or laxatives with this drug (e.g., sorbitol, magnesium hydroxide) -Patients should be advised to speak to healthcare provider if pregnant, intend to become pregnant, or are breastfeeding. Data sources include IBM Watson Micromedex (updated 3 Mar 2021), Cerner Multum™ (updated 1 Mar 2021), ASHP (updated 3 Mar 2021) and others. Sodium polystyrene sulfonate is not absorbed from the gastrointestinal tract. Appropriate measures should be taken to correct serum electrolytes (potassium, calcium, magnesium), and the resin should be removed from the alimentary tract by appropriate use of laxatives or enemas. Sodium polystyrene sulfonate has the potential to bind other drugs. Oral The average total daily adult dose of Sodium Polystyrene Sulfonate is 15 g to 60 g, administered as a 15-g dose (four level teaspoons), one to four times daily.

Lmu Dean Of Students, Overbury Design Manager, Barcelona Sponsor Qatar Airways, Invalids Benefit Nz, Hurricane Ike Eye Path, Burger King Drive Thru Singapore, Tim Hortons Franchise Usa,